Current Challenge: Platform trial designs
It is known that sometimes at the design stage of a clinical trial, simulations are conducted to better understand the operating characteristics of the design. Based on a simulated data set, the challenge is to visualise characteristics of the design to answer questions such as
- How can we investigate the effectiveness of early stopping for futility?
- What is the relationship between the quality of the surrogate endpoint and the average number of patients enrolled? Is there an interaction with futility stopping and treatment effect scenario?
- How do FWER and FWER_BA differ from each other with respect to treatment effect scenario and maximum number of cohorts?
- Can you find other interesting patterns in the data?
* NOTE to download a single data set as a csv file, click on the raw button and save the file. The following link describes the process in further detail