Our award for statistical excellence in the pharmaceutical industry is made jointly with the Royal Statistician Society (RSS) every year.
The aim of the award is to recognise an outstanding level of influence in the application of an existing statistical practice, or an innovation, that has strengthened the quality and efficiency of investigations in the pharmaceutical industry.
We look for entries that have demonstrated one or more of the following:
Nominees can be based anywhere in the world and do not need to be a member of PSI or the RSS. The award is presented at the annual PSI Conference.
Entries are now being accepted for the 2025 Award for Statistical Excellence in the Pharmaceutical Industry, presented jointly by the Royal Statistical Society and PSI.
This award celebrates a piece of work that has successfully met the needs of researchers and investigators through either the application of statistical practices to new areas or advancements in the design of investigations.
Last year’s winner was the GSK Biostatistics team for their innovative use of Bayesian Dynamic Borrowing in a commercial setting. They synthesised new and existing data to enhance efficiency while upholding rigorous standards for regulatory decision-making.
The 2025 award will be presented at PSI’s annual conference, scheduled to be held in London from 8–11 June.
The deadline for entries is Tuesday 1 April 2025.
Further information and the entry form are available on the RSS webpage.
Lisa Hampson was presented with the PSI / RSS Award for Statistical Excellence in the Pharmaceutical Industry. She was nominated for her work on: "Improving the assessment of the probability of success in drug development: A holistic framework encompassing statistical significance, regulatory approval, and market access". Distinguishing it from existing approaches, this framework adopts a broader definition of ‘success’ that bridges statistical significance, clinical relevance, benefit-risk assessments, regulatory alignment, and market access as well as technical development, quality and compliance considerations.
This approach was endorsed by the Novartis Innovation Management Board, chaired by the company’s CEO, in September 2020 and has since then formally been rolled out across the entire portfolio.
In 2022, the PSI/RSS award was presented to a team of biostatisticians and statistical engineers from the healthcare company Roche, in collaboration with the University of Bath. Their winning entry was focused on ‘Standard and reference-based conditional mean imputation (methodology and open-source software)’. The team comprising of Marcel Wolbers, Alessandro Noci, Paul Delmar, Craig Gower-Page, Sean Yiu (of Roche) and Jonathan W. Bartlett (of the University of Bath) were praised by the judges for their innovative approach.
The project addressed the need of trial statisticians in the pharmaceutical industry to fully align their analysis strategy with the targeted estimand and flexible missing data assumptions for clinical trials with continuous longitudinal outcomes. The team present a novel imputation procedure which is fully deterministic (i.e. free of Monte Carlo error) and provides treatment effect estimates consistent with the Bayesian approach as well as reliable frequentist and inference with accurate standard error estimation and type I error control. The companion open-source R package ‘rbmi’ is a flexible toolbox to implement these methods in practice.
Chrissie Fletcher, Chair of PSI, said: ‘The PSI/RSS Statistical Excellence in the Pharmaceutical Industry Award is a significant achievement and recognition of a new statistical innovation created to advance drug development. Well done to the team at Roche who have applied innovative statistical thinking to a common issue in clinical trials relating to missing data and also provided a new R package to implement the methodology.’
Stian Westlake, RSS CEO, added: ‘The team are to be congratulated for this outstanding piece of work which could potentially be a big game-changer for the industry.’
In 2023, Dr Satrajit Roychoudhury of Pfizer won the award for his significant impact in developing, implementing and disseminating efficient statistical methodology in four distinct areas:
For his work on COVID-19 vaccines, he has recognised the urgent need to evaluate and identify a vaccine, but also to enable communication of findings to end users. The end result was one of the first Bayesian Phase III trials that has led to regulatory approval. For many researchers, developing novel methodology ends with acceptance of a manuscript or when the methodology is used in practice. Dr Roychoudhury has gone well beyond that and made it his mission to also educate the wider community on these methods.
Chrissie Fletcher, chair of PSI, said: 'Many congratulations to Satrajit for this significant achievement and well deserved recognition for his statistical excellence in the Pharmaceutical Industry. It is truly outstanding to implement and disseminate efficient statistical methodology in not just one, but four, important and diverse areas. An amazing accomplishment, well done.'
Dr Andrew Garrett, president of the RSS, commenting on the news said: 'Congratulations to Satrajit who should be applauded for the breadth and depth of his contributions. His work on Covid-19 vaccines clearly illustrates impact - notably how Bayesian methods can be used in a confirmatory setting to support regulatory review and approval.'
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
The book club’s usual focus is to read and discuss professional development books. In this short format event you can more easily develop you career without the commitment of reading the whole book - simply listen to the 1-hour long podcast before joining the interactive session on 21 May.
This webinar is organised by the RWD SIG and the Historical Data SIG. We will review recent methods, applications, and tools of integrating subject-level-data from clinical trial with external data using Bayesian methods and/or causal inference methods.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This will be a 45 minute webinar which will explain the topic presented in the published paper, ‘Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance’. There will be 15 minutes for a panel Q&A with some of the authors following the presentation.
This 1-hour webinar will be an opportunity to hear about the methodology and first results of the iRISE consortium. iRISE is working towards a better understanding of reproducibility and the interventions that work to improve it. At the end of the presentation there will also be the opportunity to ask questions.
This one-day event focuses on the comprehensive management of transitioning to R/Open-Source, addressing the challenges and providing actionable insights. Attendees will participate in sessions covering essential topics such as training best practices, creating strategic plans, making the case to senior management, and managing both statistical and programming aspects of the transition.
This course is aimed at biostatisticians with no or some pediatric drug development experience who are interested to further their understanding. We will give you an introduction to the pediatric drug development landscape. This will include identifying the key regulations and processes governing pediatric development, a discussion on the needs and challenges when conducting pediatric research and a focus on the ways to overcome these challenges from a statistical perspective.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
The program will feature insightful sessions led by distinguished invited speakers, alongside a poster session showcasing the latest advancements in the field. Further details will be provided.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
The Institute of Cancer Research are seeking to appoint a Research Group Leader to join The CRUK Clinical Trials and Statistics Unit at the ICR.
This is an exciting, new opportunity for an experienced Statistician looking to take the next step in their career. Offered as a remote or hybrid position aligned with our site in Harrogate, North Yorkshire.
