We are a group of statisticians working at CROs and pharmaceutical industry supporting preclinical drug discovery on animal and cell based experiments. As a group, our focus is on diverse range of preclinical topics such as;
We organise webinars and workshops on topics and methodological developments in preclinical research and now have a list of over 50 affiliates on our e-mail distribution list.
Core Committee (L-R): (* not present in the picture)
| Name | Company/Institution |
| Denise Federico | Evotec |
| Luc Essermeant | Sanofi |
| Eloisa Brook | GSK (chair) |
| Dorothee Tamarelle | Sanofi |
| Fetene Tekle | Janssen |
| Bernd Igl* | Boehringer Ingelheim |
| Ezgi Tanriver-Ayder* | GSK |
| Sarah Vandepaer* | GSK |
| Helena Geys* | Janssen |
We see our mission as bridging preclinical knowledge and expertise within the pharmaceutical industry and academia to provide a forum to collaborate, discuss and advance statistical topics related to Research, Discovery (including efficacy models), Regulatory and Investigative Toxicology/Safety Assessment. We also hope to encourage the development of relevant statistical methodologies and promote the involvement of statisticians in these areas.
Find out more about us and our objectives in our video overview:
PSI Pre-clinical Special Interest Group has a
series of regular FREE webinars dealing with statistical topics faced in
pre-clinical and related fields. The presentations run for an hour, with
approximately 45 min presentation and a Q&A session in the remaining time.
See section below for details of this webinars. Please note that
these events take place online via Zoom, and have a limited number of places
available.
The PSI Pre-Clinical Special Interest Group seminars for 2025 are planned as follows:
Date | Title | Presenter | |
19 March 2025 | AI in Medicinal Products | Dr Liam Childs, AI working group lead - Paul Ehrlich Institute | To access video on demand, click here |
| 24 June 2025 | Methodology and first results of the iRISE (improving Reproducibility In SciencE) consortium | Rachel Heyard | To register, from April 28th, click here |
| 14 October 2025 | tbd | tbd |
The PSI Pre-Clinical Special Interest Group seminars for 2024 were as follows:
Date | Title | Presenter | |
26 March 2024 | Mixed-Level OMARS Designs for Quantitative and Categorical Factors: Theory and Application | Professor Peter Goos, KU Leuven | To access video on demand, click here |
| 8 October 2024 | Efficient R&D: SVEM and Advanced DOE in Preclinical Toxicity Testing | Phil Kay and Chandra Ramnarayanan, JMP | To access video on demand, click here |
| 26 November 2024 | Virtual Control Groups in Toxicity Studies | Lea Vaas, Bayer | To access video on demand, click here |
We plan a 2025 workshop in Verona, Italy, Oct 7-8 (tbc). More info to come !
We held our first face-to-face workshop since 2019 in Paris this year. It was wonderful to connect with old and new faces.There was great engagement in the sessions; we all learnt something and had fun too!
Day | Title | Presenter(s) |
1 | Application of experimental design in animal research: theory and practice | Simon Bate, GSK |
| 2 | Analysing Pre-clinical experiments | Odile Coudert, Ipsen & Bernard Franq, GSK |
| Statistics in Toxicology | Philip Jarvis, Novartis & David Lovell, University of London |
Please email us if you are interested in contributing to PSI Preclinical SIG or would like to join our mailing list.
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
The book club’s usual focus is to read and discuss professional development books. In this short format event you can more easily develop you career without the commitment of reading the whole book - simply listen to the 1-hour long podcast before joining the interactive session on 21 May.
This webinar is organised by the RWD SIG and the Historical Data SIG. We will review recent methods, applications, and tools of integrating subject-level-data from clinical trial with external data using Bayesian methods and/or causal inference methods.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This will be a 45 minute webinar which will explain the topic presented in the published paper, ‘Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance’. There will be 15 minutes for a panel Q&A with some of the authors following the presentation.
This 1-hour webinar will be an opportunity to hear about the methodology and first results of the iRISE consortium. iRISE is working towards a better understanding of reproducibility and the interventions that work to improve it. At the end of the presentation there will also be the opportunity to ask questions.
This one-day event focuses on the comprehensive management of transitioning to R/Open-Source, addressing the challenges and providing actionable insights. Attendees will participate in sessions covering essential topics such as training best practices, creating strategic plans, making the case to senior management, and managing both statistical and programming aspects of the transition.
This course is aimed at biostatisticians with no or some pediatric drug development experience who are interested to further their understanding. We will give you an introduction to the pediatric drug development landscape. This will include identifying the key regulations and processes governing pediatric development, a discussion on the needs and challenges when conducting pediatric research and a focus on the ways to overcome these challenges from a statistical perspective.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
The program will feature insightful sessions led by distinguished invited speakers, alongside a poster session showcasing the latest advancements in the field. Further details will be provided.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
The Institute of Cancer Research are seeking to appoint a Research Group Leader to join The CRUK Clinical Trials and Statistics Unit at the ICR.
This is an exciting, new opportunity for an experienced Statistician looking to take the next step in their career. Offered as a remote or hybrid position aligned with our site in Harrogate, North Yorkshire.
The BioMarin internship programme will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, whilst gaining an insight into the pharmaceutical/biotech industry.
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