Dates: Mon.9th, Tues.10th, Thurs.12th & Fri.13th October 2023 Time: 09:00-12:00 BST (each day) Location: Online Speakers: Jonathan Bartlett and James Carpenter (LSHTM)
Who is this event intended for? This course is intended for clinical trial statisticians who are interested in learning more about statistical methods for handling missing data in clinical trial analyses. What is the benefit of attending? By the end of the course participants will be familiar with the key concepts (e.g. missing at random) and statistical methods (e.g. multiple imputation) relevant when estimating treatment effects in trials where some data are missing.
Cost
Early Bird PSI Members = £320+VAT Early Bird Non-Members = £430*+VAT *Please note: Early Bird prices expire at 17:00 on Friday 8th September.
Standard PSI Members = £360+VAT Standard Non-Members = £470*+VAT
*Please note: Non-Member rates include PSI membership until 31 Dec. 2024.
This course will introduce participants to the key concepts and methods relevant for analysing clinical trials when some data are missing. We will describe missing data assumptions and Rubin’s framework for classifying them, based on missing completely at random, missing at random (MAR), and missing not at random, and what these imply when missingness is due to dropout or the occurrence of intercurrent events. We will describe the use of mixed models and multiple imputation to handle missingness under MAR, and finally discuss methods for conducting missing data sensitivity analyses, including reference based imputation methods.
The course will cover:
Introduction to estimands and missing data in trials; review of missing data assumptions & terminology (e.g. missing at random)
Performing analyses under missing at random for continuous outcome data, using mixed models and multiple imputation (including consideration of retrieved dropout multiple imputation)
Performing analyses under missing at random for binary data, using full conditional specification for multiple imputation with a GEE analysis model
Sensitivity analyses using multiple imputation, including reference based imputation methods
Please note: Each of the above will be presented in a one hour lecture, followed by a two hour interactive computer practical. Computer practicals will be taught using R and so having R or R Studio installed on your personal laptop/computer is required to participate in the practicals.
Speaker details
Speaker
Biography
Jonathan Bartlett LSHTM
Jonathan Bartlett is a Professor in Medical Statistics at the London School of Hygiene & Tropical Medicine.
His research interests are focused around missing data and causal inference methods, and more recently, how these can be applied to target different estimands in clinical trials. He has held previous positions at AstraZeneca and the University of Bath, and maintains a blog thestatsgeek.com
James Carpenter LSHTM
James Carpenter is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine, and MRC Investigator in trials methodology at the MRC CTU at UCL.
His principal research interests are coping with missing data in clinical trials and complex hierarchical models, estimands, sensitivity analysis, meta-analysis and novel trial designs.
Dates: Mon.9th, Tues.10th, Thurs.12th & Fri.13th October 2023 Time: 09:00-12:00 BST (each day) Location: Online Speakers: Jonathan Bartlett and James Carpenter (LSHTM)
Who is this event intended for? This course is intended for clinical trial statisticians who are interested in learning more about statistical methods for handling missing data in clinical trial analyses. What is the benefit of attending? By the end of the course participants will be familiar with the key concepts (e.g. missing at random) and statistical methods (e.g. multiple imputation) relevant when estimating treatment effects in trials where some data are missing.
Cost
Early Bird PSI Members = £320+VAT Early Bird Non-Members = £430*+VAT *Please note: Early Bird prices expire at 17:00 on Friday 8th September.
Standard PSI Members = £360+VAT Standard Non-Members = £470*+VAT
*Please note: Non-Member rates include PSI membership until 31 Dec. 2024.
This course will introduce participants to the key concepts and methods relevant for analysing clinical trials when some data are missing. We will describe missing data assumptions and Rubin’s framework for classifying them, based on missing completely at random, missing at random (MAR), and missing not at random, and what these imply when missingness is due to dropout or the occurrence of intercurrent events. We will describe the use of mixed models and multiple imputation to handle missingness under MAR, and finally discuss methods for conducting missing data sensitivity analyses, including reference based imputation methods.
The course will cover:
Introduction to estimands and missing data in trials; review of missing data assumptions & terminology (e.g. missing at random)
Performing analyses under missing at random for continuous outcome data, using mixed models and multiple imputation (including consideration of retrieved dropout multiple imputation)
Performing analyses under missing at random for binary data, using full conditional specification for multiple imputation with a GEE analysis model
Sensitivity analyses using multiple imputation, including reference based imputation methods
Please note: Each of the above will be presented in a one hour lecture, followed by a two hour interactive computer practical. Computer practicals will be taught using R and so having R or R Studio installed on your personal laptop/computer is required to participate in the practicals.
Speaker details
Speaker
Biography
Jonathan Bartlett LSHTM
Jonathan Bartlett is a Professor in Medical Statistics at the London School of Hygiene & Tropical Medicine.
His research interests are focused around missing data and causal inference methods, and more recently, how these can be applied to target different estimands in clinical trials. He has held previous positions at AstraZeneca and the University of Bath, and maintains a blog thestatsgeek.com
James Carpenter LSHTM
James Carpenter is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine, and MRC Investigator in trials methodology at the MRC CTU at UCL.
His principal research interests are coping with missing data in clinical trials and complex hierarchical models, estimands, sensitivity analysis, meta-analysis and novel trial designs.
Dates: Mon.9th, Tues.10th, Thurs.12th & Fri.13th October 2023 Time: 09:00-12:00 BST (each day) Location: Online Speakers: Jonathan Bartlett and James Carpenter (LSHTM)
Who is this event intended for? This course is intended for clinical trial statisticians who are interested in learning more about statistical methods for handling missing data in clinical trial analyses. What is the benefit of attending? By the end of the course participants will be familiar with the key concepts (e.g. missing at random) and statistical methods (e.g. multiple imputation) relevant when estimating treatment effects in trials where some data are missing.
Cost
Early Bird PSI Members = £320+VAT Early Bird Non-Members = £430*+VAT *Please note: Early Bird prices expire at 17:00 on Friday 8th September.
Standard PSI Members = £360+VAT Standard Non-Members = £470*+VAT
*Please note: Non-Member rates include PSI membership until 31 Dec. 2024.
This course will introduce participants to the key concepts and methods relevant for analysing clinical trials when some data are missing. We will describe missing data assumptions and Rubin’s framework for classifying them, based on missing completely at random, missing at random (MAR), and missing not at random, and what these imply when missingness is due to dropout or the occurrence of intercurrent events. We will describe the use of mixed models and multiple imputation to handle missingness under MAR, and finally discuss methods for conducting missing data sensitivity analyses, including reference based imputation methods.
The course will cover:
Introduction to estimands and missing data in trials; review of missing data assumptions & terminology (e.g. missing at random)
Performing analyses under missing at random for continuous outcome data, using mixed models and multiple imputation (including consideration of retrieved dropout multiple imputation)
Performing analyses under missing at random for binary data, using full conditional specification for multiple imputation with a GEE analysis model
Sensitivity analyses using multiple imputation, including reference based imputation methods
Please note: Each of the above will be presented in a one hour lecture, followed by a two hour interactive computer practical. Computer practicals will be taught using R and so having R or R Studio installed on your personal laptop/computer is required to participate in the practicals.
Speaker details
Speaker
Biography
Jonathan Bartlett LSHTM
Jonathan Bartlett is a Professor in Medical Statistics at the London School of Hygiene & Tropical Medicine.
His research interests are focused around missing data and causal inference methods, and more recently, how these can be applied to target different estimands in clinical trials. He has held previous positions at AstraZeneca and the University of Bath, and maintains a blog thestatsgeek.com
James Carpenter LSHTM
James Carpenter is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine, and MRC Investigator in trials methodology at the MRC CTU at UCL.
His principal research interests are coping with missing data in clinical trials and complex hierarchical models, estimands, sensitivity analysis, meta-analysis and novel trial designs.
Dates: Mon.9th, Tues.10th, Thurs.12th & Fri.13th October 2023 Time: 09:00-12:00 BST (each day) Location: Online Speakers: Jonathan Bartlett and James Carpenter (LSHTM)
Who is this event intended for? This course is intended for clinical trial statisticians who are interested in learning more about statistical methods for handling missing data in clinical trial analyses. What is the benefit of attending? By the end of the course participants will be familiar with the key concepts (e.g. missing at random) and statistical methods (e.g. multiple imputation) relevant when estimating treatment effects in trials where some data are missing.
Cost
Early Bird PSI Members = £320+VAT Early Bird Non-Members = £430*+VAT *Please note: Early Bird prices expire at 17:00 on Friday 8th September.
Standard PSI Members = £360+VAT Standard Non-Members = £470*+VAT
*Please note: Non-Member rates include PSI membership until 31 Dec. 2024.
This course will introduce participants to the key concepts and methods relevant for analysing clinical trials when some data are missing. We will describe missing data assumptions and Rubin’s framework for classifying them, based on missing completely at random, missing at random (MAR), and missing not at random, and what these imply when missingness is due to dropout or the occurrence of intercurrent events. We will describe the use of mixed models and multiple imputation to handle missingness under MAR, and finally discuss methods for conducting missing data sensitivity analyses, including reference based imputation methods.
The course will cover:
Introduction to estimands and missing data in trials; review of missing data assumptions & terminology (e.g. missing at random)
Performing analyses under missing at random for continuous outcome data, using mixed models and multiple imputation (including consideration of retrieved dropout multiple imputation)
Performing analyses under missing at random for binary data, using full conditional specification for multiple imputation with a GEE analysis model
Sensitivity analyses using multiple imputation, including reference based imputation methods
Please note: Each of the above will be presented in a one hour lecture, followed by a two hour interactive computer practical. Computer practicals will be taught using R and so having R or R Studio installed on your personal laptop/computer is required to participate in the practicals.
Speaker details
Speaker
Biography
Jonathan Bartlett LSHTM
Jonathan Bartlett is a Professor in Medical Statistics at the London School of Hygiene & Tropical Medicine.
His research interests are focused around missing data and causal inference methods, and more recently, how these can be applied to target different estimands in clinical trials. He has held previous positions at AstraZeneca and the University of Bath, and maintains a blog thestatsgeek.com
James Carpenter LSHTM
James Carpenter is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine, and MRC Investigator in trials methodology at the MRC CTU at UCL.
His principal research interests are coping with missing data in clinical trials and complex hierarchical models, estimands, sensitivity analysis, meta-analysis and novel trial designs.
Dates: Mon.9th, Tues.10th, Thurs.12th & Fri.13th October 2023 Time: 09:00-12:00 BST (each day) Location: Online Speakers: Jonathan Bartlett and James Carpenter (LSHTM)
Who is this event intended for? This course is intended for clinical trial statisticians who are interested in learning more about statistical methods for handling missing data in clinical trial analyses. What is the benefit of attending? By the end of the course participants will be familiar with the key concepts (e.g. missing at random) and statistical methods (e.g. multiple imputation) relevant when estimating treatment effects in trials where some data are missing.
Cost
Early Bird PSI Members = £320+VAT Early Bird Non-Members = £430*+VAT *Please note: Early Bird prices expire at 17:00 on Friday 8th September.
Standard PSI Members = £360+VAT Standard Non-Members = £470*+VAT
*Please note: Non-Member rates include PSI membership until 31 Dec. 2024.
This course will introduce participants to the key concepts and methods relevant for analysing clinical trials when some data are missing. We will describe missing data assumptions and Rubin’s framework for classifying them, based on missing completely at random, missing at random (MAR), and missing not at random, and what these imply when missingness is due to dropout or the occurrence of intercurrent events. We will describe the use of mixed models and multiple imputation to handle missingness under MAR, and finally discuss methods for conducting missing data sensitivity analyses, including reference based imputation methods.
The course will cover:
Introduction to estimands and missing data in trials; review of missing data assumptions & terminology (e.g. missing at random)
Performing analyses under missing at random for continuous outcome data, using mixed models and multiple imputation (including consideration of retrieved dropout multiple imputation)
Performing analyses under missing at random for binary data, using full conditional specification for multiple imputation with a GEE analysis model
Sensitivity analyses using multiple imputation, including reference based imputation methods
Please note: Each of the above will be presented in a one hour lecture, followed by a two hour interactive computer practical. Computer practicals will be taught using R and so having R or R Studio installed on your personal laptop/computer is required to participate in the practicals.
Speaker details
Speaker
Biography
Jonathan Bartlett LSHTM
Jonathan Bartlett is a Professor in Medical Statistics at the London School of Hygiene & Tropical Medicine.
His research interests are focused around missing data and causal inference methods, and more recently, how these can be applied to target different estimands in clinical trials. He has held previous positions at AstraZeneca and the University of Bath, and maintains a blog thestatsgeek.com
James Carpenter LSHTM
James Carpenter is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine, and MRC Investigator in trials methodology at the MRC CTU at UCL.
His principal research interests are coping with missing data in clinical trials and complex hierarchical models, estimands, sensitivity analysis, meta-analysis and novel trial designs.
Dates: Mon.9th, Tues.10th, Thurs.12th & Fri.13th October 2023 Time: 09:00-12:00 BST (each day) Location: Online Speakers: Jonathan Bartlett and James Carpenter (LSHTM)
Who is this event intended for? This course is intended for clinical trial statisticians who are interested in learning more about statistical methods for handling missing data in clinical trial analyses. What is the benefit of attending? By the end of the course participants will be familiar with the key concepts (e.g. missing at random) and statistical methods (e.g. multiple imputation) relevant when estimating treatment effects in trials where some data are missing.
Cost
Early Bird PSI Members = £320+VAT Early Bird Non-Members = £430*+VAT *Please note: Early Bird prices expire at 17:00 on Friday 8th September.
Standard PSI Members = £360+VAT Standard Non-Members = £470*+VAT
*Please note: Non-Member rates include PSI membership until 31 Dec. 2024.
This course will introduce participants to the key concepts and methods relevant for analysing clinical trials when some data are missing. We will describe missing data assumptions and Rubin’s framework for classifying them, based on missing completely at random, missing at random (MAR), and missing not at random, and what these imply when missingness is due to dropout or the occurrence of intercurrent events. We will describe the use of mixed models and multiple imputation to handle missingness under MAR, and finally discuss methods for conducting missing data sensitivity analyses, including reference based imputation methods.
The course will cover:
Introduction to estimands and missing data in trials; review of missing data assumptions & terminology (e.g. missing at random)
Performing analyses under missing at random for continuous outcome data, using mixed models and multiple imputation (including consideration of retrieved dropout multiple imputation)
Performing analyses under missing at random for binary data, using full conditional specification for multiple imputation with a GEE analysis model
Sensitivity analyses using multiple imputation, including reference based imputation methods
Please note: Each of the above will be presented in a one hour lecture, followed by a two hour interactive computer practical. Computer practicals will be taught using R and so having R or R Studio installed on your personal laptop/computer is required to participate in the practicals.
Speaker details
Speaker
Biography
Jonathan Bartlett LSHTM
Jonathan Bartlett is a Professor in Medical Statistics at the London School of Hygiene & Tropical Medicine.
His research interests are focused around missing data and causal inference methods, and more recently, how these can be applied to target different estimands in clinical trials. He has held previous positions at AstraZeneca and the University of Bath, and maintains a blog thestatsgeek.com
James Carpenter LSHTM
James Carpenter is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine, and MRC Investigator in trials methodology at the MRC CTU at UCL.
His principal research interests are coping with missing data in clinical trials and complex hierarchical models, estimands, sensitivity analysis, meta-analysis and novel trial designs.
Upcoming Events
Joint PSI/EFSPI Visualisation SIG 'Wonderful Wednesday' Webinars
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
Topic: R Package Basics.
Our monthly webinar series allows attendees to gain practical knowledge and skills in open-source coding and tools, with a focus on applications in the pharmaceutical industry. This month’s session, “R Package Basics,” will introduce the fundamentals of working with R packages—covering how to install, load, and manage them effectively to support data analysis and reproducible research. The session will provide a solid starting point, clarify common misconceptions, and offer valuable resources for continued learning.
Date: Ongoing 6 month cycle beginning late April/early May 2026
Are you a member of PSI looking to further your career or help develop others - why not sign up to the PSI Mentoring scheme? You can expand your network, improve your leadership skills and learn from more senior colleagues in the industry.
PSI Book Club Lunch and Learn: Communicating with Clarity and Confidence
If you have read Ros Atkins’ book The Art of Explanation or want to listen to the BBC’s ‘Communicator in Chief’, you are invited to join the PSI Book Club Lunch and Learn, to discuss the content and application with the author, Ros Atkins. Having written the book within the context of the news industry, Ros is keen to hear how we have applied the ideas as statisticians within drug development and clinical trials. There will be dedicated time during the webinar to ASK THE AUTHOR any questions – don’t miss out on this exclusive PSI Book Club event!
Haven’t read the book yet? Pick up a copy today and join us.
Explanation - identifying and communicating what we want to say - is described as an art, in the title of his book. However, the creativity comes from Ros’ discernment in identifying and describing a clear step-by-step process to follow and practice. Readers can learn Ros’ rules, developed and polished throughout his career as a journalist, to help communicate complex written or spoken information clearly.
PSI Training Course: Effective Leadership – the keys to growing your leadership capabilities
This course will consist of three online half-day workshops. The first will be aimed at building trust, the backbone of leadership and a key to becoming effective. This is key to building a solid foundation.
The second will be on improving communication as a technical leader. This workshop will focus on communication strategies for different stakeholders and will involve tips on effective communication and how to develop the skills of active listening, coaching and what improv can teach us about good communication.
The final workshop will bring these two components together to help leaders become more influential. This will also focus on how to use Steven Covey’s 7-Habits, in particular Habits 4, 5 and 6, which are called the habits of communication.
The workshops will be interactive, allowing you to practice the concepts discussed. There will be plenty of time for questions and discussion. There will also be reflective time where you can think about what you are learning and how you might experiment with it.