Video-on-Demand Library

23 October 2024

Margaret Gamalo, Cordula Zeller, Patrick Schlömer, Dali Zhou

This webinar discusses the complexities and opportunities of clinical trials with hierarchical composite endpoints, covering topics such as win odds, win ratio, net benefit as well as regulatory considerations when defining hierarchical composite endpoints. This webinar starts with a general introduction to hierarchical composite endpoints and an overview of common analysis methods including win ratio, win odds, and net benefit. Then, the practical considerations are illustrated through case studies from clinical trials in heart failure and chronic kidney disease. The webinar concludes with a discussion and a Q&A.

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