Video-on-Demand Library

03 June 2025

Mark Baird, Helle Lynggaard, Sue McKendrick, David Wright

The expert authors of a recent paper introduce the game-changing concepts of the “estimand framework”, "intercurrent events", and the estimand thinking process. In this beginner-friendly session, you'll learn, step-by-step, how to apply estimand thinking to your trials, leading to clearer objectives and more meaningful results.   There is a practical case study – a bioequivalence trial – to illustrate how the estimand framework can eliminate ambiguity and bring greater transparency to the key clinical questions you're investigating. Beyond this specific example, there is discussion around the broader impact of estimands on various clinical pharmacology trials. 

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