Date: Tuesday 19th November 2024 Time: 14:00-15:30 GMT | 15:00-16:30 CET Location: Online via Zoom Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch
Who is this event intended for? Applied statisticians, and people genuinely interested in applying state-of-the-art statistical methodology.
What is the benefit of attending? Increased understanding and insights in causal inference principles and methodology.
Registration
This event is free to attend for both Members of PSI and Non-Members. To register your place, please click here.
Overview
In this webinar, three speakers will share their perspective on the using of causal inference methodology in the analysis of RCT data. The audience will be presented with ideas and opportunities on why and how to apply causal inference principles / techniques in their work. And more importantly how causal approaches can help evaluating evidence for answers to causal-by-nature scientific questions.
First, Kaspar Rufibach (Merck) will share his perspectives on opportunities to apply causal methods. Next, Susan Gruber (TL revolution) will discuss targeted learning as a framework to address causal questions and the importance of sensitivity analyses. Finally, Florian Lasch (EMA) will discuss both the importance of the causal inference angle in determining estimands, and will discuss a case study.
The webinar will end with a panel discussion.
Speaker
Biography
Abstract
Kaspar Rufibach
Kaspar Rufibach is a biostatistician who is passionate about supporting statisticians and drug developers to continuously challenge the status quo, with the aim of improving the drug development process, making it more efficient, and enabling access.
Kaspar has co-founded and co-leads the special interest group “Estimands in oncology” which has (as of August 2024) more than 100 members from 50 institutions globally. He has also co-founded and co-leads the EFSPI statistical methodology leader group which has 14 members from 14 companies. He regularly interacts with regulators globally on various joint projects.
Kaspar’s research interests are methods to optimize study designs, platform trials, advanced survival analysis, probability of success, estimands and causal inference, and estimation of treatment effects in subgroups. Kaspar received training and worked as a statistician at the Universities of Bern, Stanford, and Zurich. From 2012 until 2024 he worked at Roche before joining Merck KGaA in October 2024 to co-lead its Advanced Biostatistical Science group.
I will start with providing a few examples of very valid scientific questions in drug development that typically ask for causal answers, but which are routinely answered in ad-hoc ways that rarely allow for a causal interpretation. Further reasons why I believe a clinical biostatistician needs to know about causal inference will be given. I will conclude with a call to apply and develop statistical and causal inference methodology to fill the gap between valid causal questions and routine ad-hoc answers.
Susan Gruber
Susan Gruber, co-founder of TL Revolution and Founder of Putnam Data Sciences, is a biostatistician and computer scientist specializing in causal inference and predictive modeling. Her work focuses on improving methods and tools for generating robust real-world evidence to support biopharmaceutical and medical decision-making through Targeted Learning. Her tmle R package on CRAN has over 70,000 downloads worldwide.
Targeted Learning is a framework that combines causal inference, statistics, and machine learning to address complex issues in analyzing data from randomized controlled trials and studies that incorporate real-world data. This talk provides a high-level introduction to the Targeted Learning Estimation Roadmap, statistical analysis using Targeted Maximum Likelihood Estimation (TMLE), and the role of sensitivity analysis to assess the level of support for drawing a substantive conclusion from the study findings.
Florian Lasch
Florian is a Biostatistician with a degree in mathematics and a PhD from Hannover Medical School. Florian works as a Biostatistics Specialist at the European Medicines Agency, providing scientific support to development and evaluation throughout all stages of marketing authorisation assessments of medicinal products, and leads the ACT EU Priority Action on Clinical Trial Methodologies and the EMA Estimands Implementation Group.
The estimands framework facilitates the application of thinking and methodology developed in the causal inference community to the design and analysis of clinical trials. This presentation will reflect on the opportunities and challenges of applying causal inference methodology to clinical trials. A case study in Alzheimer’s Disease where the intercurrent event ‘initiation of symptomatic medication’ is handled with a hypothetical strategy will illustrate the key points.
Scientific Meetings
Joint PSI/EFSPI Causal Inference SIG Webinar: Opportunities in applying a causal inference framework during the analysis of an RCT
Date: Tuesday 19th November 2024 Time: 14:00-15:30 GMT | 15:00-16:30 CET Location: Online via Zoom Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch
Who is this event intended for? Applied statisticians, and people genuinely interested in applying state-of-the-art statistical methodology.
What is the benefit of attending? Increased understanding and insights in causal inference principles and methodology.
Registration
This event is free to attend for both Members of PSI and Non-Members. To register your place, please click here.
Overview
In this webinar, three speakers will share their perspective on the using of causal inference methodology in the analysis of RCT data. The audience will be presented with ideas and opportunities on why and how to apply causal inference principles / techniques in their work. And more importantly how causal approaches can help evaluating evidence for answers to causal-by-nature scientific questions.
First, Kaspar Rufibach (Merck) will share his perspectives on opportunities to apply causal methods. Next, Susan Gruber (TL revolution) will discuss targeted learning as a framework to address causal questions and the importance of sensitivity analyses. Finally, Florian Lasch (EMA) will discuss both the importance of the causal inference angle in determining estimands, and will discuss a case study.
The webinar will end with a panel discussion.
Speaker
Biography
Abstract
Kaspar Rufibach
Kaspar Rufibach is a biostatistician who is passionate about supporting statisticians and drug developers to continuously challenge the status quo, with the aim of improving the drug development process, making it more efficient, and enabling access.
Kaspar has co-founded and co-leads the special interest group “Estimands in oncology” which has (as of August 2024) more than 100 members from 50 institutions globally. He has also co-founded and co-leads the EFSPI statistical methodology leader group which has 14 members from 14 companies. He regularly interacts with regulators globally on various joint projects.
Kaspar’s research interests are methods to optimize study designs, platform trials, advanced survival analysis, probability of success, estimands and causal inference, and estimation of treatment effects in subgroups. Kaspar received training and worked as a statistician at the Universities of Bern, Stanford, and Zurich. From 2012 until 2024 he worked at Roche before joining Merck KGaA in October 2024 to co-lead its Advanced Biostatistical Science group.
I will start with providing a few examples of very valid scientific questions in drug development that typically ask for causal answers, but which are routinely answered in ad-hoc ways that rarely allow for a causal interpretation. Further reasons why I believe a clinical biostatistician needs to know about causal inference will be given. I will conclude with a call to apply and develop statistical and causal inference methodology to fill the gap between valid causal questions and routine ad-hoc answers.
Susan Gruber
Susan Gruber, co-founder of TL Revolution and Founder of Putnam Data Sciences, is a biostatistician and computer scientist specializing in causal inference and predictive modeling. Her work focuses on improving methods and tools for generating robust real-world evidence to support biopharmaceutical and medical decision-making through Targeted Learning. Her tmle R package on CRAN has over 70,000 downloads worldwide.
Targeted Learning is a framework that combines causal inference, statistics, and machine learning to address complex issues in analyzing data from randomized controlled trials and studies that incorporate real-world data. This talk provides a high-level introduction to the Targeted Learning Estimation Roadmap, statistical analysis using Targeted Maximum Likelihood Estimation (TMLE), and the role of sensitivity analysis to assess the level of support for drawing a substantive conclusion from the study findings.
Florian Lasch
Florian is a Biostatistician with a degree in mathematics and a PhD from Hannover Medical School. Florian works as a Biostatistics Specialist at the European Medicines Agency, providing scientific support to development and evaluation throughout all stages of marketing authorisation assessments of medicinal products, and leads the ACT EU Priority Action on Clinical Trial Methodologies and the EMA Estimands Implementation Group.
The estimands framework facilitates the application of thinking and methodology developed in the causal inference community to the design and analysis of clinical trials. This presentation will reflect on the opportunities and challenges of applying causal inference methodology to clinical trials. A case study in Alzheimer’s Disease where the intercurrent event ‘initiation of symptomatic medication’ is handled with a hypothetical strategy will illustrate the key points.
Training Courses
Joint PSI/EFSPI Causal Inference SIG Webinar: Opportunities in applying a causal inference framework during the analysis of an RCT
Date: Tuesday 19th November 2024 Time: 14:00-15:30 GMT | 15:00-16:30 CET Location: Online via Zoom Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch
Who is this event intended for? Applied statisticians, and people genuinely interested in applying state-of-the-art statistical methodology.
What is the benefit of attending? Increased understanding and insights in causal inference principles and methodology.
Registration
This event is free to attend for both Members of PSI and Non-Members. To register your place, please click here.
Overview
In this webinar, three speakers will share their perspective on the using of causal inference methodology in the analysis of RCT data. The audience will be presented with ideas and opportunities on why and how to apply causal inference principles / techniques in their work. And more importantly how causal approaches can help evaluating evidence for answers to causal-by-nature scientific questions.
First, Kaspar Rufibach (Merck) will share his perspectives on opportunities to apply causal methods. Next, Susan Gruber (TL revolution) will discuss targeted learning as a framework to address causal questions and the importance of sensitivity analyses. Finally, Florian Lasch (EMA) will discuss both the importance of the causal inference angle in determining estimands, and will discuss a case study.
The webinar will end with a panel discussion.
Speaker
Biography
Abstract
Kaspar Rufibach
Kaspar Rufibach is a biostatistician who is passionate about supporting statisticians and drug developers to continuously challenge the status quo, with the aim of improving the drug development process, making it more efficient, and enabling access.
Kaspar has co-founded and co-leads the special interest group “Estimands in oncology” which has (as of August 2024) more than 100 members from 50 institutions globally. He has also co-founded and co-leads the EFSPI statistical methodology leader group which has 14 members from 14 companies. He regularly interacts with regulators globally on various joint projects.
Kaspar’s research interests are methods to optimize study designs, platform trials, advanced survival analysis, probability of success, estimands and causal inference, and estimation of treatment effects in subgroups. Kaspar received training and worked as a statistician at the Universities of Bern, Stanford, and Zurich. From 2012 until 2024 he worked at Roche before joining Merck KGaA in October 2024 to co-lead its Advanced Biostatistical Science group.
I will start with providing a few examples of very valid scientific questions in drug development that typically ask for causal answers, but which are routinely answered in ad-hoc ways that rarely allow for a causal interpretation. Further reasons why I believe a clinical biostatistician needs to know about causal inference will be given. I will conclude with a call to apply and develop statistical and causal inference methodology to fill the gap between valid causal questions and routine ad-hoc answers.
Susan Gruber
Susan Gruber, co-founder of TL Revolution and Founder of Putnam Data Sciences, is a biostatistician and computer scientist specializing in causal inference and predictive modeling. Her work focuses on improving methods and tools for generating robust real-world evidence to support biopharmaceutical and medical decision-making through Targeted Learning. Her tmle R package on CRAN has over 70,000 downloads worldwide.
Targeted Learning is a framework that combines causal inference, statistics, and machine learning to address complex issues in analyzing data from randomized controlled trials and studies that incorporate real-world data. This talk provides a high-level introduction to the Targeted Learning Estimation Roadmap, statistical analysis using Targeted Maximum Likelihood Estimation (TMLE), and the role of sensitivity analysis to assess the level of support for drawing a substantive conclusion from the study findings.
Florian Lasch
Florian is a Biostatistician with a degree in mathematics and a PhD from Hannover Medical School. Florian works as a Biostatistics Specialist at the European Medicines Agency, providing scientific support to development and evaluation throughout all stages of marketing authorisation assessments of medicinal products, and leads the ACT EU Priority Action on Clinical Trial Methodologies and the EMA Estimands Implementation Group.
The estimands framework facilitates the application of thinking and methodology developed in the causal inference community to the design and analysis of clinical trials. This presentation will reflect on the opportunities and challenges of applying causal inference methodology to clinical trials. A case study in Alzheimer’s Disease where the intercurrent event ‘initiation of symptomatic medication’ is handled with a hypothetical strategy will illustrate the key points.
Journal Club
Joint PSI/EFSPI Causal Inference SIG Webinar: Opportunities in applying a causal inference framework during the analysis of an RCT
Date: Tuesday 19th November 2024 Time: 14:00-15:30 GMT | 15:00-16:30 CET Location: Online via Zoom Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch
Who is this event intended for? Applied statisticians, and people genuinely interested in applying state-of-the-art statistical methodology.
What is the benefit of attending? Increased understanding and insights in causal inference principles and methodology.
Registration
This event is free to attend for both Members of PSI and Non-Members. To register your place, please click here.
Overview
In this webinar, three speakers will share their perspective on the using of causal inference methodology in the analysis of RCT data. The audience will be presented with ideas and opportunities on why and how to apply causal inference principles / techniques in their work. And more importantly how causal approaches can help evaluating evidence for answers to causal-by-nature scientific questions.
First, Kaspar Rufibach (Merck) will share his perspectives on opportunities to apply causal methods. Next, Susan Gruber (TL revolution) will discuss targeted learning as a framework to address causal questions and the importance of sensitivity analyses. Finally, Florian Lasch (EMA) will discuss both the importance of the causal inference angle in determining estimands, and will discuss a case study.
The webinar will end with a panel discussion.
Speaker
Biography
Abstract
Kaspar Rufibach
Kaspar Rufibach is a biostatistician who is passionate about supporting statisticians and drug developers to continuously challenge the status quo, with the aim of improving the drug development process, making it more efficient, and enabling access.
Kaspar has co-founded and co-leads the special interest group “Estimands in oncology” which has (as of August 2024) more than 100 members from 50 institutions globally. He has also co-founded and co-leads the EFSPI statistical methodology leader group which has 14 members from 14 companies. He regularly interacts with regulators globally on various joint projects.
Kaspar’s research interests are methods to optimize study designs, platform trials, advanced survival analysis, probability of success, estimands and causal inference, and estimation of treatment effects in subgroups. Kaspar received training and worked as a statistician at the Universities of Bern, Stanford, and Zurich. From 2012 until 2024 he worked at Roche before joining Merck KGaA in October 2024 to co-lead its Advanced Biostatistical Science group.
I will start with providing a few examples of very valid scientific questions in drug development that typically ask for causal answers, but which are routinely answered in ad-hoc ways that rarely allow for a causal interpretation. Further reasons why I believe a clinical biostatistician needs to know about causal inference will be given. I will conclude with a call to apply and develop statistical and causal inference methodology to fill the gap between valid causal questions and routine ad-hoc answers.
Susan Gruber
Susan Gruber, co-founder of TL Revolution and Founder of Putnam Data Sciences, is a biostatistician and computer scientist specializing in causal inference and predictive modeling. Her work focuses on improving methods and tools for generating robust real-world evidence to support biopharmaceutical and medical decision-making through Targeted Learning. Her tmle R package on CRAN has over 70,000 downloads worldwide.
Targeted Learning is a framework that combines causal inference, statistics, and machine learning to address complex issues in analyzing data from randomized controlled trials and studies that incorporate real-world data. This talk provides a high-level introduction to the Targeted Learning Estimation Roadmap, statistical analysis using Targeted Maximum Likelihood Estimation (TMLE), and the role of sensitivity analysis to assess the level of support for drawing a substantive conclusion from the study findings.
Florian Lasch
Florian is a Biostatistician with a degree in mathematics and a PhD from Hannover Medical School. Florian works as a Biostatistics Specialist at the European Medicines Agency, providing scientific support to development and evaluation throughout all stages of marketing authorisation assessments of medicinal products, and leads the ACT EU Priority Action on Clinical Trial Methodologies and the EMA Estimands Implementation Group.
The estimands framework facilitates the application of thinking and methodology developed in the causal inference community to the design and analysis of clinical trials. This presentation will reflect on the opportunities and challenges of applying causal inference methodology to clinical trials. A case study in Alzheimer’s Disease where the intercurrent event ‘initiation of symptomatic medication’ is handled with a hypothetical strategy will illustrate the key points.
Webinars
Joint PSI/EFSPI Causal Inference SIG Webinar: Opportunities in applying a causal inference framework during the analysis of an RCT
Date: Tuesday 19th November 2024 Time: 14:00-15:30 GMT | 15:00-16:30 CET Location: Online via Zoom Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch
Who is this event intended for? Applied statisticians, and people genuinely interested in applying state-of-the-art statistical methodology.
What is the benefit of attending? Increased understanding and insights in causal inference principles and methodology.
Registration
This event is free to attend for both Members of PSI and Non-Members. To register your place, please click here.
Overview
In this webinar, three speakers will share their perspective on the using of causal inference methodology in the analysis of RCT data. The audience will be presented with ideas and opportunities on why and how to apply causal inference principles / techniques in their work. And more importantly how causal approaches can help evaluating evidence for answers to causal-by-nature scientific questions.
First, Kaspar Rufibach (Merck) will share his perspectives on opportunities to apply causal methods. Next, Susan Gruber (TL revolution) will discuss targeted learning as a framework to address causal questions and the importance of sensitivity analyses. Finally, Florian Lasch (EMA) will discuss both the importance of the causal inference angle in determining estimands, and will discuss a case study.
The webinar will end with a panel discussion.
Speaker
Biography
Abstract
Kaspar Rufibach
Kaspar Rufibach is a biostatistician who is passionate about supporting statisticians and drug developers to continuously challenge the status quo, with the aim of improving the drug development process, making it more efficient, and enabling access.
Kaspar has co-founded and co-leads the special interest group “Estimands in oncology” which has (as of August 2024) more than 100 members from 50 institutions globally. He has also co-founded and co-leads the EFSPI statistical methodology leader group which has 14 members from 14 companies. He regularly interacts with regulators globally on various joint projects.
Kaspar’s research interests are methods to optimize study designs, platform trials, advanced survival analysis, probability of success, estimands and causal inference, and estimation of treatment effects in subgroups. Kaspar received training and worked as a statistician at the Universities of Bern, Stanford, and Zurich. From 2012 until 2024 he worked at Roche before joining Merck KGaA in October 2024 to co-lead its Advanced Biostatistical Science group.
I will start with providing a few examples of very valid scientific questions in drug development that typically ask for causal answers, but which are routinely answered in ad-hoc ways that rarely allow for a causal interpretation. Further reasons why I believe a clinical biostatistician needs to know about causal inference will be given. I will conclude with a call to apply and develop statistical and causal inference methodology to fill the gap between valid causal questions and routine ad-hoc answers.
Susan Gruber
Susan Gruber, co-founder of TL Revolution and Founder of Putnam Data Sciences, is a biostatistician and computer scientist specializing in causal inference and predictive modeling. Her work focuses on improving methods and tools for generating robust real-world evidence to support biopharmaceutical and medical decision-making through Targeted Learning. Her tmle R package on CRAN has over 70,000 downloads worldwide.
Targeted Learning is a framework that combines causal inference, statistics, and machine learning to address complex issues in analyzing data from randomized controlled trials and studies that incorporate real-world data. This talk provides a high-level introduction to the Targeted Learning Estimation Roadmap, statistical analysis using Targeted Maximum Likelihood Estimation (TMLE), and the role of sensitivity analysis to assess the level of support for drawing a substantive conclusion from the study findings.
Florian Lasch
Florian is a Biostatistician with a degree in mathematics and a PhD from Hannover Medical School. Florian works as a Biostatistics Specialist at the European Medicines Agency, providing scientific support to development and evaluation throughout all stages of marketing authorisation assessments of medicinal products, and leads the ACT EU Priority Action on Clinical Trial Methodologies and the EMA Estimands Implementation Group.
The estimands framework facilitates the application of thinking and methodology developed in the causal inference community to the design and analysis of clinical trials. This presentation will reflect on the opportunities and challenges of applying causal inference methodology to clinical trials. A case study in Alzheimer’s Disease where the intercurrent event ‘initiation of symptomatic medication’ is handled with a hypothetical strategy will illustrate the key points.
Careers Meetings
Joint PSI/EFSPI Causal Inference SIG Webinar: Opportunities in applying a causal inference framework during the analysis of an RCT
Date: Tuesday 19th November 2024 Time: 14:00-15:30 GMT | 15:00-16:30 CET Location: Online via Zoom Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch
Who is this event intended for? Applied statisticians, and people genuinely interested in applying state-of-the-art statistical methodology.
What is the benefit of attending? Increased understanding and insights in causal inference principles and methodology.
Registration
This event is free to attend for both Members of PSI and Non-Members. To register your place, please click here.
Overview
In this webinar, three speakers will share their perspective on the using of causal inference methodology in the analysis of RCT data. The audience will be presented with ideas and opportunities on why and how to apply causal inference principles / techniques in their work. And more importantly how causal approaches can help evaluating evidence for answers to causal-by-nature scientific questions.
First, Kaspar Rufibach (Merck) will share his perspectives on opportunities to apply causal methods. Next, Susan Gruber (TL revolution) will discuss targeted learning as a framework to address causal questions and the importance of sensitivity analyses. Finally, Florian Lasch (EMA) will discuss both the importance of the causal inference angle in determining estimands, and will discuss a case study.
The webinar will end with a panel discussion.
Speaker
Biography
Abstract
Kaspar Rufibach
Kaspar Rufibach is a biostatistician who is passionate about supporting statisticians and drug developers to continuously challenge the status quo, with the aim of improving the drug development process, making it more efficient, and enabling access.
Kaspar has co-founded and co-leads the special interest group “Estimands in oncology” which has (as of August 2024) more than 100 members from 50 institutions globally. He has also co-founded and co-leads the EFSPI statistical methodology leader group which has 14 members from 14 companies. He regularly interacts with regulators globally on various joint projects.
Kaspar’s research interests are methods to optimize study designs, platform trials, advanced survival analysis, probability of success, estimands and causal inference, and estimation of treatment effects in subgroups. Kaspar received training and worked as a statistician at the Universities of Bern, Stanford, and Zurich. From 2012 until 2024 he worked at Roche before joining Merck KGaA in October 2024 to co-lead its Advanced Biostatistical Science group.
I will start with providing a few examples of very valid scientific questions in drug development that typically ask for causal answers, but which are routinely answered in ad-hoc ways that rarely allow for a causal interpretation. Further reasons why I believe a clinical biostatistician needs to know about causal inference will be given. I will conclude with a call to apply and develop statistical and causal inference methodology to fill the gap between valid causal questions and routine ad-hoc answers.
Susan Gruber
Susan Gruber, co-founder of TL Revolution and Founder of Putnam Data Sciences, is a biostatistician and computer scientist specializing in causal inference and predictive modeling. Her work focuses on improving methods and tools for generating robust real-world evidence to support biopharmaceutical and medical decision-making through Targeted Learning. Her tmle R package on CRAN has over 70,000 downloads worldwide.
Targeted Learning is a framework that combines causal inference, statistics, and machine learning to address complex issues in analyzing data from randomized controlled trials and studies that incorporate real-world data. This talk provides a high-level introduction to the Targeted Learning Estimation Roadmap, statistical analysis using Targeted Maximum Likelihood Estimation (TMLE), and the role of sensitivity analysis to assess the level of support for drawing a substantive conclusion from the study findings.
Florian Lasch
Florian is a Biostatistician with a degree in mathematics and a PhD from Hannover Medical School. Florian works as a Biostatistics Specialist at the European Medicines Agency, providing scientific support to development and evaluation throughout all stages of marketing authorisation assessments of medicinal products, and leads the ACT EU Priority Action on Clinical Trial Methodologies and the EMA Estimands Implementation Group.
The estimands framework facilitates the application of thinking and methodology developed in the causal inference community to the design and analysis of clinical trials. This presentation will reflect on the opportunities and challenges of applying causal inference methodology to clinical trials. A case study in Alzheimer’s Disease where the intercurrent event ‘initiation of symptomatic medication’ is handled with a hypothetical strategy will illustrate the key points.
Upcoming Events
PSI Introduction to Industry Training (ITIT) Course - 2025/2026
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
Joint PSI/EFSPI Visualisation SIG 'Wonderful Wednesday' Webinars
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
PSI Book Club Webinar: Atomic Habits - The Science of Getting Your Act Together
The book club’s usual focus is to read and discuss professional development books. In this short format event you can more easily develop you career without the commitment of reading the whole book - simply listen to the 1-hour long podcast before joining the interactive session on 21 May.
PSI Webinar: Methods and tools integrating clinical trial evidence with historical or real-world data, Bayesian borrowing, and causal inference
This webinar is organised by the RWD SIG and the Historical Data SIG. We will review recent methods, applications, and tools of integrating subject-level-data from clinical trial with external data using Bayesian methods and/or causal inference methods.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
PSI Webinar: Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance
This will be a 45 minute webinar which will explain the topic presented in the published paper, ‘Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance’. There will be 15 minutes for a panel Q&A with some of the authors following the presentation.
PSI Webinar: Methodology and first results of the iRISE (improving Reproducibility In SciencE) consortium
This 1-hour webinar will be an opportunity to hear about the methodology and first results of the iRISE consortium. iRISE is working towards a better understanding of reproducibility and the interventions that work to improve it. At the end of the presentation there will also be the opportunity to ask questions.
One-day Event: Change Management for Moving to R/Open-Source
This one-day event focuses on the comprehensive management of transitioning to R/Open-Source, addressing the challenges and providing actionable insights. Attendees will participate in sessions covering essential topics such as training best practices, creating strategic plans, making the case to senior management, and managing both statistical and programming aspects of the transition.
PSI Book Club - The Art of Explanation: How to Communicate with Clarity and Confidence
Develop your non-technical skills by reading The Art of Explanation by Ros Atkins and joining the Sept-Dec 2025 book club. You will be invited to join facilitated discussions of the concepts and ideas and apply skills from the book in-between sessions.
This course is aimed at biostatisticians with no or some pediatric drug development experience who are interested to further their understanding. We will give you an introduction to the pediatric drug development landscape. This will include identifying the key regulations and processes governing pediatric development, a discussion on the needs and challenges when conducting pediatric research and a focus on the ways to overcome these challenges from a statistical perspective.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This is an exciting, new opportunity for an experienced Statistician looking to take the next step in their career. Offered as a remote or hybrid position aligned with our site in Harrogate, North Yorkshire.
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