Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Scientific Meetings
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Training Courses
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Journal Club
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Webinars
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Careers Meetings
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Upcoming Events
PSI Training Course: Introduction to Machine Learning
This course is aimed at clinical trial statisticians who are new to or with limited experience of machine learning. Attendees will learn about a range of topics in machine learning, including practical sessions in R.
Joint PSI/EFSPI Visualisation SIG 'Wonderful Wednesday' Webinars
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
The event will open with an overview on drug development in women’s health from a clinician perspective. This talk is followed by talks about statistical challenges when planning IVF studies and analysing the menstrual cycles.
This webinar will provide an overview of surrogacy for licensing and reimbursement. In turn, the need of extensions of the SPIRIT and CONSORT statement will be defined and outlined, with case studies to support.
Joint PSI/EFSPI Pre-Clinical SIG Webinar: Virtual Control Groups in Toxicity Studies
Lea Vaas will present how replacement of concurrent control animals by Virtual Control Groups (VCGs) in systemic toxicity studies may help in contributing to the 3R's principle of animal experimentation: Reduce, Refine, Replace.
Joint PSI/EFSPI Data Science SIG Webinar: Developing Digital Measures (Digital Biomarkers) in Drug Development – insights from Mobilise D consortium
We will share a brief overview of what Mobilise D is and why it is an important step stone in the development of digital biomarkers, and how Mobilise D outputs can be relevant for you.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
PSI Introduction to Industry Training (ITIT) Course - 2024/2025
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
Statisticians in the Pharmaceutical Industry Executive Office: c/o MCI UK Ltd | Unit 24/22 South | Building 4000 | Langstone Park| Langstone Road | Havant | PO9 1SA | UK