Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Scientific Meetings
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Training Courses
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Journal Club
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Webinars
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Careers Meetings
PSI Pre-Clinical SIG Webinar: Therioepistemology - Rethinking how we conduct animal-based experimentation
Date: Tuesday 4th October 2022 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: Brianna Gaskill (Novartis)
Who is this event intended for? Colleagues working in in-vivo research. What is the benefit of attending? Attendees have the opportunity to learn how knowledge can be gained from animal research.
Registration
You can now register for this event. Registration fees are as follows:
- Members of PSI = Free of charge
- Non-Members of PSI = Free of charge
To register for the session, please click here.
Overview
In recent years, the scientific community has finally become more generally aware of the current reproducibility and translatability crisis. Some of this awareness has come from the recent NIH initiative on “Enhancing rigor, transparency, and translatability in animal research” starting a paradigm shift around certain themes. This shift can be characterized at the micro level as a shift from asking “what have we controlled for in this model?” to asking “what have we chosen to ignore in this model, and at what cost?” At the macro level, it is a shift from viewing animals as tools (the furry test tube), to viewing them as patients in an equivalent human medical study, this includes providing for an animals welfare as well as experimental design and analysis techniques. Colleagues and I feel that we are witnessing the birth of a new discipline, which we have termed Therioepistemology, or the study of how knowledge is gained from animal research. In this talk, I’ll outline six questions that help critically evaluate animal-based biomedical research from a therioepistemological perspective. Ultimately, by formalizing therioepistemology as a discipline, we can begin to discuss best practices that will improve the reproducibility and translatability of animal-based research, with concomitant benefits in terms of human health, animal well-being, and scientific quality.
Speaker details
Speaker
Biography
Brianna Gaskill, PhD Novartis
Brianna received her BS from Kansas State University and PhD in Animal Behavior and Well-being from Purdue University. She completed a postdoctoral position at Charles River after graduation, then returned to Purdue as a faculty member in 2014 and was awarded tenure in 2020. Her research has focused on developing new animal welfare assessment methodologies, rodent well-being, and elucidating the scientific impact of welfare problems in animal based research. She recently started a new position at Novartis as their 3Rs scientist where she will work closely with disease area scientists to apply 3Rs strategies to improve animal welfare and drug discovery. Her research contributions have been acknowledged by receiving awards from the NC3R’s, the Swiss Laboratory Animal Science Association, and the International Society for Applied Ethology.
Upcoming Events
PSI Introduction to Industry Training (ITIT) Course - 2025/2026
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
Joint PSI/EFSPI Visualisation SIG 'Wonderful Wednesday' Webinars
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
PSI Book Club Webinar: Atomic Habits - The Science of Getting Your Act Together
The book club’s usual focus is to read and discuss professional development books. In this short format event you can more easily develop you career without the commitment of reading the whole book - simply listen to the 1-hour long podcast before joining the interactive session on 21 May.
PSI Webinar: Methods and tools integrating clinical trial evidence with historical or real-world data, Bayesian borrowing, and causal inference
This webinar is organised by the RWD SIG and the Historical Data SIG. We will review recent methods, applications, and tools of integrating subject-level-data from clinical trial with external data using Bayesian methods and/or causal inference methods.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
PSI Webinar: Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance
This will be a 45 minute webinar which will explain the topic presented in the published paper, ‘Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance’. There will be 15 minutes for a panel Q&A with some of the authors following the presentation.
PSI Webinar: Methodology and first results of the iRISE (improving Reproducibility In SciencE) consortium
This 1-hour webinar will be an opportunity to hear about the methodology and first results of the iRISE consortium. iRISE is working towards a better understanding of reproducibility and the interventions that work to improve it. At the end of the presentation there will also be the opportunity to ask questions.
One-day PSI/PHUSE Event: Change Management for Moving to R/Open-Source
This one-day event focuses on the comprehensive management of transitioning to R/Open-Source, addressing the challenges and providing actionable insights. Attendees will participate in sessions covering essential topics such as training best practices, creating strategic plans, making the case to senior management, and managing both statistical and programming aspects of the transition.
PSI Book Club - The Art of Explanation: How to Communicate with Clarity and Confidence
Develop your non-technical skills by reading The Art of Explanation by Ros Atkins and joining the Sept-Dec 2025 book club. You will be invited to join facilitated discussions of the concepts and ideas and apply skills from the book in-between sessions.
This course is aimed at biostatisticians with no or some pediatric drug development experience who are interested to further their understanding. We will give you an introduction to the pediatric drug development landscape. This will include identifying the key regulations and processes governing pediatric development, a discussion on the needs and challenges when conducting pediatric research and a focus on the ways to overcome these challenges from a statistical perspective.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
The program will feature insightful sessions led by distinguished invited speakers, alongside a poster session showcasing the latest advancements in the field. Further details will be provided.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This is an exciting, new opportunity for an experienced Statistician looking to take the next step in their career. Offered as a remote or hybrid position aligned with our site in Harrogate, North Yorkshire.
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