Event

PSI Journal Club: Missing Data

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Date:
 Thursday 13th November 2025
Time: 16:00-17:00 GMT | 17:00-18:00 CET | 11:00-12:00 EST
Presenters: Cesar Torres and Suzie Cro
Chair: Kevin Ding
Location: Online via Zoom

Who is this event intended for? Anyone interested in hearing more about missing data.

What is the benefit of attending? o gain a better understanding about missing data: tipping point methodology to evaluate sensitivity to potential violations in missing data assumptions and the handling of partially observed trial data after treatment withdrawal.

This event is free to attend for both Members of PSI and Non-Members.

To register, please click here

Overview

Please join us to hear Cesar Torres (FDA) and Suzie Cro (Imperial College London) present their recent work.

1. Cesar Torres, Gregory Levin, Daniel Rubin, William Koh, Rebecca Chiu, Thomas Permutt: A Tipping Point Method to Evaluate Sensitivity to Potential Violations in Missing Data Assumptions - https://onlinelibrary.wiley.com/doi/10.1002/pst.70002 

2. Suzie Cro, James H. Roger, James R. Carpenter: Handling Partially Observed Trial Data After Treatment Withdrawal: Introducing Retrieved Dropout Reference-Base Centred Multiple Imputation - https://onlinelibrary.wiley.com/doi/10.1002/pst.2416

Post presentation discussions to information to follow.

PSI Journal Club is sponsored by Wiley. For each of these published papers there will be a 20 minute presentation by author followed by a 10 minute discussion.

Papers will be made available to view prior to the meeting and presentation slides will be available a week before the JC. Journal subscribers can access papers at any time. Audio recordings will be available shortly after the JC to download from the PSI website.

The meetings are open to both PSI and non-PSI members

Speaker details

Speaker

Biography

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Kevin Ding, Ocular Therapeutix
Kevin completed his graduate studies in biostatistics from University of Massachusetts at Amherst. He has over 16 years experience working as a biostatistician in various pharmaceutical companies, including J&J, Novartis and AstraZeneca. He is currently working as a statistical consultant for Ocular Therapeutix. Kevin's research interests include estimand, missing data imputation and adaptive design. He presented the topic of missing data and estimand in JSM and PSI webinar before. The methods in these presentations were applied and implemented in several phase 3 clinical trials he worked on.
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Cesar Torres, FDA
Cesar completed his graduate studies at the University of Washington’s Department of Biostatistics. He now works at the FDA’s Center for Drug Evaluation and Research in the Office of Biostatistics (OB) as the acting team leader for the statistical review team supporting the Division of Rheumatology and Transplant Medicine. He also serves as a member of the OB estimands working group, as well as the chair of the OB missing data working group. Cesar’s research interests include estimands, missing data, the evaluation of safety and benefit-risk, and finite sample properties of select statistical methodologies.
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Suzie Cro, Imperial College London
Dr Suzie Cro is Head of Trial Methodology and co-Head of the Statistics section at Imperial Clinical Trials Unit (ICTU), Imperial College London. She has over 15 years’ experience in the design and analysis of clinical trials and other interventional studies across clinical areas including dermatology, musculoskeletal, dementia and opiate addiction. Her core statistical research interests include translating the ICH-E9-R1 addendum on estimands and sensitivity analysis in clinical trials into best practice for researchers and patients and the public, handling missing data and transparency in the statistical analysis of clinical trials. She obtained her PhD in medical statistical from the London School of Hygiene and Tropical Medicine.

 

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