Abstract Submissions 2026

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The PSI Scientific Committee would like to say a huge thanks to everyone who submitted an abstract for oral or poster consideration. We were overwhelmed with the amount received and have had to make some difficult decisions!

Individual oral abstracts can be found in the document library below as well as a full abstract book. 

All abstracts will also be available to view on the conference app.

Submissions for 2027 Conference will open in September 2026 so look out for information about this after the conference in June. 

Title Type Size
15_June_1100_BOIN_vs_BLRM_a_systematic_performance_comparison_in_phase_1_dose_escalation pdf 109 KB Download15_June_1100_BOIN_vs_BLRM_a_systematic_performance_comparison_in_phase_1_dose_escalation
15_June_1100_Dont_Get_Distracted_by_Noise_Simulations_Done_Right pdf 193 KB Download15_June_1100_Dont_Get_Distracted_by_Noise_Simulations_Done_Right
15_June_1100_Dose_finding_in_late_phase_Bayesian_trials pdf 106 KB Download15_June_1100_Dose_finding_in_late_phase_Bayesian_trials
15_June_1100_Early_Phase_Dose_Finding_Designs_for_CAR_T_cell_Therapies pdf 107 KB Download15_June_1100_Early_Phase_Dose_Finding_Designs_for_CAR_T_cell_Therapies
15_June_1100_Patient_Focused_Drug_Development_SIG_Tolerability_PROs_across_the_drug_development_lifecycle pdf 187 KB Download15_June_1100_Patient_Focused_Drug_Development_SIG_Tolerability_PROs_across_the_drug_development_lifecycle
15_June_1100_The_impact_of_backfilling_on_early_phase_dose_optimisation_trials_in_oncology pdf 109 KB Download15_June_1100_The_impact_of_backfilling_on_early_phase_dose_optimisation_trials_in_oncology
15_June_1100_The_river_keeps_moving_How_statisticians_can_survive_and_flourish_in_a_world_that_never_stands_still pdf 171 KB Download15_June_1100_The_river_keeps_moving_How_statisticians_can_survive_and_flourish_in_a_world_that_never_stands_still
15_June_1330_Academic_Industry_Collaboration_and_Connection pdf 107 KB Download15_June_1330_Academic_Industry_Collaboration_and_Connection
15_June_1330_AI_ML_SIG_Practical_AI_and_Developments_in_Machine_Learning pdf 115 KB Download15_June_1330_AI_ML_SIG_Practical_AI_and_Developments_in_Machine_Learning
15_June_1330_All_PICOs_Great_and_Small_Dealing_with_small_subpopulations_in_the_EU_HTA_Landscape pdf 124 KB Download15_June_1330_All_PICOs_Great_and_Small_Dealing_with_small_subpopulations_in_the_EU_HTA_Landscape
15_June_1330_Estimands_for_the_Percentage_Change_from_Baseline_Guidance_for_Clinical_Trials pdf 109 KB Download15_June_1330_Estimands_for_the_Percentage_Change_from_Baseline_Guidance_for_Clinical_Trials
15_June_1330_Evaluating_Estimand_Implementation_in_Clinical_Trials_in_the_UK_and_Beyond pdf 122 KB Download15_June_1330_Evaluating_Estimand_Implementation_in_Clinical_Trials_in_the_UK_and_Beyond
15_June_1330_How_about_those_estimands_for_my_cross_over_study pdf 109 KB Download15_June_1330_How_about_those_estimands_for_my_cross_over_study
15_June_1330_Not_Just_Another_Estimands_Talk_Practical_Strategies_for_Cross_Functional_Engagement_to_Ensure_Meaningful_Fit_for_Purpose_Estimands pdf 107 KB Download15_June_1330_Not_Just_Another_Estimands_Talk_Practical_Strategies_for_Cross_Functional_Engagement_to_Ensure_Meaningful_Fit_for_Purpose_Estimands
15_June_1330_Workshop_Navigating_EU_HTA_From_pivotal_trial_to_evidence_networks_based_on_first_experiences pdf 130 KB Download15_June_1330_Workshop_Navigating_EU_HTA_From_pivotal_trial_to_evidence_networks_based_on_first_experiences
15_June_1545_A_spectrum_of_causal_estimands_differences_in_dosing_adherence_patterns pdf 126 KB Download15_June_1545_A_spectrum_of_causal_estimands_differences_in_dosing_adherence_patterns
15_June_1545_Assessing_covariate_adjusted_risk_differences_in_small_sample_trials pdf 110 KB Download15_June_1545_Assessing_covariate_adjusted_risk_differences_in_small_sample_trials
15_June_1545_Can_NI_margin_calibration_safeguard_against_invalid_results_in_an_evolving_population pdf 107 KB Download15_June_1545_Can_NI_margin_calibration_safeguard_against_invalid_results_in_an_evolving_population
15_June_1545_Data_Monitoring_Committees_Best_Practices_and_Future_Development pdf 122 KB Download15_June_1545_Data_Monitoring_Committees_Best_Practices_and_Future_Development
15_June_1545_Disentangling_Indirect_Effects_of_Vaccine_Assignment_from_Other_Causal_Pathways_in_Cluster-Randomized_Trials_with_Noncompliance pdf 109 KB Download15_June_1545_Disentangling_Indirect_Effects_of_Vaccine_Assignment_from_Other_Causal_Pathways_in_Cluster-Randomized_Trials_with_Noncompliance
15_June_1545_Evaluation_of_Z_tests_to_compare_fixed_time_survival_probabilities_using_stratified_Kaplan-Meier_estimates_with_different_variance_estimators_and_weights pdf 122 KB Download15_June_1545_Evaluation_of_Z_tests_to_compare_fixed_time_survival_probabilities_using_stratified_Kaplan-Meier_estimates_with_different_variance_estimators_and_weights
15_June_1545_Incorporating_prognostic_scores_in_time_to_event_analysis pdf 107 KB Download15_June_1545_Incorporating_prognostic_scores_in_time_to_event_analysis
15_June_1545_Integrated_Decision_Theoretic_Optimisation_of_Phase_II_III_Oncology_Trials pdf 109 KB Download15_June_1545_Integrated_Decision_Theoretic_Optimisation_of_Phase_II_III_Oncology_Trials
15_June_1545_Multiple_Endpoints_in_Early_Phase_Decision_Making pdf 109 KB Download15_June_1545_Multiple_Endpoints_in_Early_Phase_Decision_Making
15_June_1545_Optimising_multiplicity_adjustment_in_clinical_trials_using_elicited_functions_of_commercial_value_and_clinical_benefit pdf 148 KB Download15_June_1545_Optimising_multiplicity_adjustment_in_clinical_trials_using_elicited_functions_of_commercial_value_and_clinical_benefit
15_June_1545_PREDOSE_Pharmacometrically_Refined_Early_phase_Dose_Optimization_design_for_Oncology_Study_Enhancement pdf 109 KB Download15_June_1545_PREDOSE_Pharmacometrically_Refined_Early_phase_Dose_Optimization_design_for_Oncology_Study_Enhancement
15_June_1545_Sensitivity_Analysis_of_Missing_Pharmacokinetic_Samples_in_a_Simulated_Study_of_Rapid_Acting_Psychedelics pdf 122 KB Download15_June_1545_Sensitivity_Analysis_of_Missing_Pharmacokinetic_Samples_in_a_Simulated_Study_of_Rapid_Acting_Psychedelics
16_June_1030_Developments_in_early_phase_dose_finding_trials pdf 123 KB Download16_June_1030_Developments_in_early_phase_dose_finding_trials
16_June_1030_From_Coders_to_Drug_Developers_The_Expanding_Role_of_Statisticians_in_the_Age_of_AI pdf 129 KB Download16_June_1030_From_Coders_to_Drug_Developers_The_Expanding_Role_of_Statisticians_in_the_Age_of_AI
16_June_1030_Implementing_ICH_E20_Designing_and_Analysing_Adaptive_Clinical_Trials pdf 179 KB Download16_June_1030_Implementing_ICH_E20_Designing_and_Analysing_Adaptive_Clinical_Trials
16_June_1030_Innovative_Statistical_Approaches_Designs_and_Predictive_Models_in_Vaccine_Clinical_Trials pdf 181 KB Download16_June_1030_Innovative_Statistical_Approaches_Designs_and_Predictive_Models_in_Vaccine_Clinical_Trials
16_June_1030_Leveraging_LLMs_to_navigate_complex_language_in_clinical_trial_informed_consents_forms pdf 124 KB Download16_June_1030_Leveraging_LLMs_to_navigate_complex_language_in_clinical_trial_informed_consents_forms
16_June_1030_Multi_Study_Causal_Forest_Improving_the_estimation_of_heterogeneous_treatment_effects_using_auxiliary_data pdf 146 KB Download16_June_1030_Multi_Study_Causal_Forest_Improving_the_estimation_of_heterogeneous_treatment_effects_using_auxiliary_data
16_June_1030_Trustworthy_AI_in_Medicine_A_Unified_Bayesian_Approach_to_Uncertainty_Performance_and_Fairness pdf 147 KB Download16_June_1030_Trustworthy_AI_in_Medicine_A_Unified_Bayesian_Approach_to_Uncertainty_Performance_and_Fairness
16_June_1030_What_if_Weve_Been_Looking_at_the_Wrong_Data_Reimagining_Clinical_Trial_Success_Prediction_using_AI pdf 123 KB Download16_June_1030_What_if_Weve_Been_Looking_at_the_Wrong_Data_Reimagining_Clinical_Trial_Success_Prediction_using_AI
16_June_1400_Assessing_the_impact_of_interim_decisions_in_group_sequential_trials pdf 107 KB Download16_June_1400_Assessing_the_impact_of_interim_decisions_in_group_sequential_trials
16_June_1400_Beyond_Chance_Randomisation_Designs_for_Innovative_Clinical_Trials pdf 129 KB Download16_June_1400_Beyond_Chance_Randomisation_Designs_for_Innovative_Clinical_Trials
16_June_1400_Framework_for_timing_interim_analyses_in_longitudinal_trials_with_missing_data pdf 163 KB Download16_June_1400_Framework_for_timing_interim_analyses_in_longitudinal_trials_with_missing_data
16_June_1400_Including_quantitative_benefit_risk_assessment_in_seamlessphase_23_designs_with_dose_selection pdf 122 KB Download16_June_1400_Including_quantitative_benefit_risk_assessment_in_seamlessphase_23_designs_with_dose_selection
16_June_1400_JCA_Insights_Unleashed_What_Statisticians_Can_Learn_from_the_first_JCA_Procedures pdf 123 KB Download16_June_1400_JCA_Insights_Unleashed_What_Statisticians_Can_Learn_from_the_first_JCA_Procedures
16_June_1400_Joint_session_by_the_Biomarkers_ESIG_and_the_Treatment_Effect_Heterogeneity_SIG pdf 129 KB Download16_June_1400_Joint_session_by_the_Biomarkers_ESIG_and_the_Treatment_Effect_Heterogeneity_SIG
16_June_1400_When_futility_is_futile_an_economic_case_for_more_pragmatism_in_late_phase_futility_stopping pdf 123 KB Download16_June_1400_When_futility_is_futile_an_economic_case_for_more_pragmatism_in_late_phase_futility_stopping
16_June_1615_A_Unified_Inference_Framework_for_Risk_Difference_and_Risk_Ratio pdf 110 KB Download16_June_1615_A_Unified_Inference_Framework_for_Risk_Difference_and_Risk_Ratio
16_June_1615_Assessing_Multiple_Endpoints_Using_a_Novel_Software_Solution_in_a_Late_Stage_Oncology_Study pdf 122 KB Download16_June_1615_Assessing_Multiple_Endpoints_Using_a_Novel_Software_Solution_in_a_Late_Stage_Oncology_Study
16_June_1615_Comparing_Conditional_Mean_and_Bayesian_Imputation_under_MAR_and_Reference-Based_Strategies_in_Rare_Disease_Trials pdf 107 KB Download16_June_1615_Comparing_Conditional_Mean_and_Bayesian_Imputation_under_MAR_and_Reference-Based_Strategies_in_Rare_Disease_Trials
16_June_1615_Developing_a_simulation_based_decision_framework_for_interpretation_of_interim_survival_data_in_oncology_trials pdf 124 KB Download16_June_1615_Developing_a_simulation_based_decision_framework_for_interpretation_of_interim_survival_data_in_oncology_trials
16_June_1615_Enhanced_reconstruction_of_pseudo_individual_patient_data_using_quadratic_programming pdf 107 KB Download16_June_1615_Enhanced_reconstruction_of_pseudo_individual_patient_data_using_quadratic_programming
16_June_1615_Fast_Fresh_Interactive_R_Dashboards_for_Statisticians_in_30_Minutes_or_Less pdf 109 KB Download16_June_1615_Fast_Fresh_Interactive_R_Dashboards_for_Statisticians_in_30_Minutes_or_Less
16_June_1615_From_Nightingale_to_Now_Why_Visualisations_Are_Still_Essential_in_The_Statisticians_Toolkit pdf 109 KB Download16_June_1615_From_Nightingale_to_Now_Why_Visualisations_Are_Still_Essential_in_The_Statisticians_Toolkit
16_June_1615_Novel_bayesian_prediction_of_event_times_using_mixture_model_for_blinded_randomized_controlled_trials pdf 122 KB Download16_June_1615_Novel_bayesian_prediction_of_event_times_using_mixture_model_for_blinded_randomized_controlled_trials
16_June_1615_The_estimand_conundrum_is_ICH_E9_R1_crystal_clear_or_are_there_still_areas_of_confusion pdf 108 KB Download16_June_1615_The_estimand_conundrum_is_ICH_E9_R1_crystal_clear_or_are_there_still_areas_of_confusion
16_June_1615_Validating_Shiny_Apps_in_Regulated_Environments_with_the_Litmusverse pdf 128 KB Download16_June_1615_Validating_Shiny_Apps_in_Regulated_Environments_with_the_Litmusverse
16_June_1615_Which_CRAN_Packages_Pharma_Can_Actually_Rely_On pdf 121 KB Download16_June_1615_Which_CRAN_Packages_Pharma_Can_Actually_Rely_On
17_June_0915_Regulatory_Hot_Topics pdf 107 KB Download17_June_0915_Regulatory_Hot_Topics
17_June_1115_A_comparison_of_approaches_to_incorporate_patient_selected_and_patient_ranked_outcomes_in_clinical_trials pdf 107 KB Download17_June_1115_A_comparison_of_approaches_to_incorporate_patient_selected_and_patient_ranked_outcomes_in_clinical_trials
17_June_1115_A_Comprehensive_Self_Adaptive_Mixture_Prior_Approach_to_Dynamic_Borrowing_from_External_Data pdf 107 KB Download17_June_1115_A_Comprehensive_Self_Adaptive_Mixture_Prior_Approach_to_Dynamic_Borrowing_from_External_Data
17_June_1115_Accelerating_Alzheimers_Research_a_modular_framework_for_exploring_Bayesian_disease_progression_models pdf 163 KB Download17_June_1115_Accelerating_Alzheimers_Research_a_modular_framework_for_exploring_Bayesian_disease_progression_models
17_June_1115_Advancing_the_Implementation_of_Safety_Methodologies pdf 130 KB Download17_June_1115_Advancing_the_Implementation_of_Safety_Methodologies
17_June_1115_Does_your_PRO_sum_it_all_up_Investigating_the_variability_in_item_specific_PRO_effects_using_random_item_slopes_regression pdf 107 KB Download17_June_1115_Does_your_PRO_sum_it_all_up_Investigating_the_variability_in_item_specific_PRO_effects_using_random_item_slopes_regression
17_June_1115_Impact_of_interval_censored_data_on_comparative_time_toevent_endpoints pdf 124 KB Download17_June_1115_Impact_of_interval_censored_data_on_comparative_time_toevent_endpoints
17_June_1115_Information_borrowing_in_Bayesian_clinical_trials_choice_of_tuning_parameters_for_the_robust_mixture prior pdf 109 KB Download17_June_1115_Information_borrowing_in_Bayesian_clinical_trials_choice_of_tuning_parameters_for_the_robust_mixture prior
17_June_1115_On_the_interplay_between_prior_weight_and_variance_of_the_robustification_component_in_Robust_Mixture_Prior_Bayesian_Dynamic_Borrowing_approach pdf 162 KB Download17_June_1115_On_the_interplay_between_prior_weight_and_variance_of_the_robustification_component_in_Robust_Mixture_Prior_Bayesian_Dynamic_Borrowing_approach
17_June_1115_Real_world_data_do_you_know_all_the_opportunities_The_key_questions_they_can_answer_and_how pdf 130 KB Download17_June_1115_Real_world_data_do_you_know_all_the_opportunities_The_key_questions_they_can_answer_and_how
17_June_1115_Timepoint_selection_for_long_term_PRO_data_modelling_in_oncology_trials pdf 108 KB Download17_June_1115_Timepoint_selection_for_long_term_PRO_data_modelling_in_oncology_trials
17_June_1235_A_ballad_of_a_Basket_trial_and_historical_information_borrowing_application_in_neurodegenerative_diseases pdf 148 KB Download17_June_1235_A_ballad_of_a_Basket_trial_and_historical_information_borrowing_application_in_neurodegenerative_diseases
17_June_1235_A_robustness_assessment_of_the_latent_variable_framework_for_composite_endpoints pdf 122 KB Download17_June_1235_A_robustness_assessment_of_the_latent_variable_framework_for_composite_endpoints
17_June_1235_Beyond_Dichotomization_Efficient_Estimation_of_Response_Rates_using_Continuous_Outcomes pdf 108 KB Download17_June_1235_Beyond_Dichotomization_Efficient_Estimation_of_Response_Rates_using_Continuous_Outcomes
17_June_1235_Efficient_modelling_of_complex_responder_endpoints_to_improve_trial_power pdf 107 KB Download17_June_1235_Efficient_modelling_of_complex_responder_endpoints_to_improve_trial_power
17_June_1235_FakeNews_Statisticians_and_the_Challenge_of_Misinformation pdf 123 KB Download17_June_1235_FakeNews_Statisticians_and_the_Challenge_of_Misinformation
17_June_1235_Forecasting_and_cost_efficient_designing_restricted_enrolment_in_clinical_trials pdf 122 KB Download17_June_1235_Forecasting_and_cost_efficient_designing_restricted_enrolment_in_clinical_trials
17_June_1235_From_Behind_the_Screen_to_Beside_Your_Team_Why_the_Office_Still_Matters pdf 123 KB Download17_June_1235_From_Behind_the_Screen_to_Beside_Your_Team_Why_the_Office_Still_Matters
17_June_1235_From_Classroom_to_Clinical_Trials_How_PSI_Schools_is_inspiring_the_next_generation_of_statisticians pdf 124 KB Download17_June_1235_From_Classroom_to_Clinical_Trials_How_PSI_Schools_is_inspiring_the_next_generation_of_statisticians
17_June_1235_From_Priors_to_Partnership_A_Bayesian_View_of_CRO_Sponsor_Collaboration pdf 107 KB Download17_June_1235_From_Priors_to_Partnership_A_Bayesian_View_of_CRO_Sponsor_Collaboration
17_June_1235_How_Statisticians_Can_Use_the_Growth_Mindset_Framework_for_Stronger_FSP_Success_In_Pharma pdf 124 KB Download17_June_1235_How_Statisticians_Can_Use_the_Growth_Mindset_Framework_for_Stronger_FSP_Success_In_Pharma
17_June_1235_Integrating_Preclinical_Insights_for_Adaptive_Dose_Escalation_in_Phase_I_Oncology_Trials pdf 124 KB Download17_June_1235_Integrating_Preclinical_Insights_for_Adaptive_Dose_Escalation_in_Phase_I_Oncology_Trials
17_June_1235_Microleadership_The_habits_of_building_leadership_behaviours pdf 109 KB Download17_June_1235_Microleadership_The_habits_of_building_leadership_behaviours
17_June_1235_Rigorous_Type_I_error_control_for_randomized_BOP2-TE_designs_under_minimal_assumptions pdf 107 KB Download17_June_1235_Rigorous_Type_I_error_control_for_randomized_BOP2-TE_designs_under_minimal_assumptions
Abstract Book pdf 670 KB DownloadAbstract Book

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