At this joint PSI/RSS journal club webinar, held on 12th July 2017, we heard two excellent presentations on the topic of Adaptive Signature Designs, followed by a fascinating discussion led by Dr Richard Simon, who founded the original methodology. Dr Richard Simon recently retired as associate director of the Division of Cancer Treatment & Diagnosis and Chief of the Computational and Systems Biology Branch at the National Cancer Institute, Maryland, USA. The meeting was chaired by Steve Gilmour, Professor of Statistics at King’s College London. Our speakers were:
Dr Zhiwei Zhang, Associate Professor of Biostatistics at the University of California, Riverside, who authored 'Subgroup Selection in Adaptive Signature Designs of Confirmatory Clinical Trials', published February 2017 in JRSS Series C, Volume 2. Co-authored by Meijuan Li, Min Lin, Guoxing Soon, Tom Greene and Changyu Shen. Please click here to view the slides.
Dr Gu Mi, Research Scientist at Eli Lilly and Company in Indianapolis, Indiana, who authored 'Enhancement of the adaptive signature design for learning and confirming in a single pivotal trial' published May 2017 in Pharmaceutical Statistics. Please click here to view the slides.
To access the recording, please visit the Video-on-Demand Library.This course is aimed at clinical trial statisticians who are new to or with limited experience of machine learning. Attendees will learn about a range of topics in machine learning, including practical sessions in R.
This webinar will explore two different approaches to Correlates of Protection in vaccine development.
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
The event will open with an overview on drug development in women’s health from a clinician perspective. This talk is followed by talks about statistical challenges when planning IVF studies and analysing the menstrual cycles.
This webinar will provide an overview of surrogacy for licensing and reimbursement. In turn, the need of extensions of the SPIRIT and CONSORT statement will be defined and outlined, with case studies to support.
Lea Vaas will present how replacement of concurrent control animals by Virtual Control Groups (VCGs) in systemic toxicity studies may help in contributing to the 3R's principle of animal experimentation: Reduce, Refine, Replace.
We will share a brief overview of what Mobilise D is and why it is an important step stone in the development of digital biomarkers, and how Mobilise D outputs can be relevant for you.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
We have exciting new opportunities available for Study Statisticians, Support Statisticians and Exploratory Statisticians at various levels.
