The aim of this course is to provide participants an understanding simulation techniques. The 2 day course includes a variety of practical examples and example code will be provided in both SAS and R.
The following topics will be covered:
• Pseudo-random number generators in SAS and R. Generating samples of univariate data: The “sample” function in R. Generating samples from distributions with specified skewness and kurtosis.
• The CDF method for generating pseudo-random data samples. Univariate nonparametric simulation using empirical CDFs. The Metropolis Hastings algorithm • Generating samples of correlated bivariate data. Restrictions on possible correlations and its implication for the NORTA method. Bivariate binary data. Correlated bivariate nonparametric simulation using convex hulls.
• Generating multivariate normal data. Multivariate non-normal data using the NORTA method. Multivariate correlated binary and ordinal data. Multivariate nonparametric simulation using density surrogates.
Dr Les Huson has more than 30 years’ experience working as a consultant biostatistician in the pharma and biotech industries, and also holds an appointment as Honorary Lecturer in Medical Statistics in the Centre for Pharmacology and Therapeutics Imperial College London. His special interests are in application of simulation techniques, and the use Bayesian methodologies, in the design and analysis of clinical trials.
PSI Webinar: Wearable Technologies - Challenges and Opportunities
Wearable technologies and digital health data offer great opportunities for studying patients functionally in real life settings. Actigraphy, for example, can be used as part of clinical trials to collect continuous movement data, but the frequency of data collection results in dense datasets requiring extensive processing and signal detection. In this webinar, a panel of expert speakers will discuss how such aspects can be addressed to help realize the promise of these technologies.
Our annual PSI Medical Statistics Careers Event, will be held online using the Career Fair Plus app on Wednesday 3rd March 2021. The event will include a live online panel discussion and a virtual exhibition session.
Discover your extraordinary potential by working as a Covance AD, Biostatistics / Senior Principal Biostatistician. You will consult in the design of complex and innovative studies & clinical trial programs as well as Leading DMC/DSMB processes.
By joining our company, in this role you will apply your skills and experience in support of developing scientifically based arguments aiming to provide fair accessibility to our company’s drugs and vaccines making a real difference in patient’s lives.
Senior Principal / Principal Biostatistician (Oncology) – FSP
Join our team as a Covance FSP Senior Principal or Principal Biostatistician. You will be assigned to one Sponsor working on Phase I and II oncology studies. Previous Lead experience essential. Office or home-based anywhere in Europe or South Africa.