BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH PRODID:-//Telerik Inc.//Sitefinity CMS 15.4//EN BEGIN:VEVENT DESCRIPTION:To be presented by Carl-Fredrik Burman &\; Lisa Hampson\nReg ulatory agencies require strong control of the Type I Error for all confir matory statistical tests. Multiplicity issues can arise for several reason s\, e.g.: the possibility of winning on two different endpoints (like PFS and OS)\, interim analyses\, or testing for effects in several patient gro ups. This course will focus on the principles underlying multiple comparis on procedures and their applications to confirmatory clinical trials. We w ill describe simple ways to construct valid multiple tests\, and will expl ore how tests can be incorporated into recycling strategies. Group-sequent ial and some common adaptive tests will also be described. Concepts will b e introduced through a combination of lectures\, exercises\, and discussio n sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.\n\nThe following topi cs will be covered:\n\n Introduction to Multiple Testing\n Recycling and graphical methods\n Group sequential and adaptive designs \n Op erating characteristics and improving them using correlations\n Using d ecision analysis to optimise multiple testing procedures \n\nRegistration\ n\n \n \n  \;\n Early bird (up to & \; including 9th April) \;\n After 9th April\n \n \n PSI Member\n  \;£\;295 + VAT\n  \;£\;345 + VAT\n \n \n Non-Membe r\n  \;£\;390 + VAT\n  \;£\;440 + VAT\n \n \n\n\nRegistration is now closed.\n\nRegistration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served bas is. Please contact psi@mci-group.com \;to reserve a room. Rooms are ch arged at £\;109.00 per room including breakfast. DTEND;VALUE=DATE:20180510 DTSTAMP:20260912T172723Z DTSTART;VALUE=DATE:20180509 LOCATION:Crowne Plaza\, London Heathrow SEQUENCE:0 SUMMARY:PSI Training Course: Multiple Testing in Confirmatory Clinical Tria ls UID:RFCALITEM639248308438852711 X-ALT-DESC;FMTTYPE=text/html:

To be presented by Carl-Fredrik Burman &\; Lisa Hampson

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Regulat ory agencies require strong control of the Type I Error for all confirmato ry statistical tests. Multiplicity issues can arise for several reasons\, e.g.: the possibility of winning on two different endpoints (like PFS and OS)\, interim analyses\, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison p rocedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests\, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be in troduced through a combination of lectures\, exercises\, and discussion se ssions where groups will focus on the issues that might be encountered whe n designing and communicating statistical tests.
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\nThe follow ing topics will be covered:

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Registration

\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n
 \;Early bird (up to &\; including 9t h April) \;After 9th April
PSI Member&n bsp\;£\;295 + VAT \;£\;345 + VAT
Non-Member \;£\;390 + VAT \;£\;440 + VAT
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\nRegistration is now closed.
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\nRegistration costs include lunch and refreshments. PSI are holding a lim ited number of hotel rooms on 8th May which will be allocated on a first c ome first served basis. Please contact psi@mci-group.com \;to reserve a room. Rooms are charged at £ \;109.00 per room including breakfast.
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