BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH PRODID:-//Telerik Inc.//Sitefinity CMS 15.4//EN BEGIN:VTIMEZONE TZID:UTC BEGIN:STANDARD DTSTART;VALUE=DATE:20250101 TZNAME:UTC TZOFFSETFROM:+0000 TZOFFSETTO:+0000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DESCRIPTION:How to find us: Novotel\, London Excel\, UK Presented by Steven A. Julious Steven is a Professor of Medical Statistics at The University of Sheffield but through his career has worked in both the academic and ph armaceutical sector and is a former editor of the journal Pharmaceutical S tatistics. \; He has an interest in applied methods for clinical trial s and has a particular interest in clinical study design and sample size e stimation. \; He has written two books one on early phase trials and o ne on sample size estimation and has also developed an App called SampSize for the estimation of sample sizes. About the course: The three most impo rtant aspects of a clinical trial are: design\, design and design. \; A sample size estimate is just one aspect of a clinical study design. \; The course describes calculations for sample size estimation in the des ign of clinical trials. It will be highlighted how the objectives of a cli nical trial will impact on sample size calculations. The course is a pract ical course and all methods will be illustrated with examples and case stu dies. \nThe following topics will be covered: Introduction to Key Concepts \n- Type I error\n- Type II error\n- Power Sample Sizes for Different Clin ical Trial Objectives - Superiority\n- Equivalence\n- Non-inferiority\n- P recision based\n- Bioequivalence\n- Pilot studies Sample Sizes for Differe nt Types of Data - Normal\n- Binary\n- Ordinal\n- Survival Clinical Trial Designs - Cross-over\n- Parallel Group \nHow Design Considerations Impact on the Sample Size - Baselines/covariates\n- Multiple endpoints Other Cons iderations when Designing a Trial - Sensitivity analysis\n- Optimising var iance estimates Considerations which Impact on the Sample Size - Adaptive designs for efficacy\n- Assessing futility\n- Sample size-re-estimation Co urse runs from: \n10:00 &ndash\; 17:30 (registration from 9:30) on Day 1\n 09:00 &ndash\; 16:30 on Day 2. Registration costs (includes lunch and refr eshments) Before 30th May 2017 PSI Members £\;495 + VAT Non-Members £\;570 + VAT (includes PSI membership for 1 year) \; After 30th May 2017 PSI Members £\;595 + VAT No n-Members £\;670 + VAT (includes PSI membership for 1 year) &nb sp\; PSI are holding a limited number of hotel rooms at an extra cost unti l the \;30th May 2017 \;which will be allocated on a first come fi rst served basis. \;Please contact the \;PSI Secretariat \;fo r more information. Registration for this course has now closed. DTEND:20170629T163000Z DTSTAMP:20260608T175804Z DTSTART:20170628T100000Z LOCATION: SEQUENCE:0 SUMMARY:Estimating Sample Sizes in Clinical Trials UID:RFCALITEM639165382845563676 X-ALT-DESC;FMTTYPE=text/html:

How to find us: Novotel\, London Excel\, UK

Presented by Steven A. Julious
Steven is a Professor of Medical Statistics at The University of Shef field but through his career has worked in both the academic and pharmaceu tical sector and is a former editor of the journal Pharmaceutical Statisti cs. \; He has an interest in applied methods for clinical trials and h as a particular interest in clinical study design and sample size estimati on. \; He has written two books one on early phase trials and one on s ample size estimation and has also developed an App called SampSize for th e estimation of sample sizes.

About the course:
The three most important aspects of a clinical trial are: design\, des ign and design. \; A sample size estimate is just one aspect of a clin ical study design. \;

The course describes calculations for sam ple size estimation in the design of clinical trials. It will be highlight ed how the objectives of a clinical trial will impact on sample size calcu lations. The course is a practical course and all methods will be illustra ted with examples and case studies.

\nThe fo llowing topics will be covered:

Introduction to Key Concept s
\n- Type I error
\n- Type II error
\n- Power

Sample Sizes for Different Clinical Trial Objectives
- Superiority
\n- Equivalence
\n- Non-inferiority
\n- Precision based
\n- Bioequivalence
\n- Pilot studies

Sample Sizes for Different Types of Data
- Normal
\n- Binary
\n- Ordinal
\n- Survival

Clinical Tri al Designs
- Cross-over
\n- Parallel Group

\nHow Design Considerations Impact on the Sample Size
- Baselines/covariates
\n- Multiple endpoints

Othe r Considerations when Designing a Trial
- Sensitivity analy sis
\n- Optimising variance estimates

Considerations w hich Impact on the Sample Size
- Adaptive designs for effic acy
\n- Assessing futility
\n- Sample size-re-estimation

Course runs from:
\n10:00 &ndash\; 17:30 (registration from 9:30) on Day 1
\n09:00 &ndash\; 16:30 on Day 2.

Registration c osts (includes lunch and refreshments)

Before 30^th May 2017

PSI Member s

£\;495 + VAT< /p>

Non-Membe rs

£\;570 + VAT (includes PSI membership for 1 year)

\;

After 3 0^th May 2017

PSI Members

£\;595 + VAT

Non-Members

£\;670 + VAT (includes PSI membership for 1 year)

\;

PSI are holding a limite d number of hotel rooms at an extra cost until the \;30^th May 2017 \;which will be allocated on a first come fir st served basis. \;Please contact the \;PSI Secretariat \;for more information.

Registration for this course has now closed.
END:VEVENT END:VCALENDAR

Before 30^th May 2017
PSI Member s	£\;495 + VAT< /p>
Non-Membe rs	£\;570 + VAT (includes PSI membership for 1 year)

After 3 0^th May 2017
PSI Members	£\;595 + VAT
Non-Members	£\;670 + VAT (includes PSI membership for 1 year)