This course will take place on Sunday 14th May from 14:00. You can register your place through the conference registration system.
Cytel Pre-Conference Course
Sample Size, Power, and Adaptive Trial Design for Late Stage Studies: A Practical Hands-on Workshop
The purpose of our workshop at PSI 2017 is to first better familiarize attendees with the underlying statistical methods, then instruct you on designing related trials of greatest interest to you and your organization. Case studies of actual adaptive trials will both illustrate the use of the methodologies and serve as hands-on design examples.
Over the course of 25 years, East® has become an industry standard platform for planning and monitoring early and later stage clinical trials. You do not have to be an East user to benefit from the workshop, but the trial design examples will use the software (provided to all who bring a PC laptop).
We begin with a trial design and software capabilities overview including:
- Sample size and power calculations
- Adjustments for multiple comparisons
- Early stopping for efficacy/futility
- Sample size re-estimation
- Adaptive dose selection
- Survival endpoints
- Enrollment/event forecasting
In the workshop's second part attendees can work through hands-on exercises using the software.
Prepared examples covering many of the stated topics will be provided, with attendees choosing which to work on. Our instruction team will coach attendees throughout the design process, including running simulations to predict likely outcomes.
2017 Workshop Instructors: Pantellis Vlachos and Yannis Jemiai
All registrants will receive the complete and latest version of East® to use for 30 days following the workshop.
Refreshments will be provided gratis.